Abstract: 2-Hydroxy-5-methylbenzaldehyde was synthesized with Cresol as the stuff, tributyl amine as the phase-transfer catalyst in Reimer-Tiemann reaction. The initial product was obtained from the steam distillation. The suitable proportion of up spread reagent has been determined through Thin-Layer Chromatography and pure product was obtained from the Column chromatography separation. Then, the characteristic function group of the product was confirmed preliminarily by qualitative analysis with 2, 4-dinitrophenylhydrazine and hydrogen sulfite sodium. The structure of product was analyzed through IR and 1H-NMR.
Keywords: Reimer-Tiemann method; Cresol; 2-Hydroxy-5-methylbenzaldehyde