This paper introduced the method of industrial engineering, the method of systematic layout planning and computer simulation technology, and its basic theoretical methods in the improvement of large supermarket chain facilities layout and its application prospect. This paper mainly expounds the common facilities layout method, systematic layout planning (SLP) method, and in combination with the basic management technology of industrial engineering discussed the application strategy of systematic layout planning method in the improvement of the chain supermarket facilities layout, work and environment, based on Flexsim simulation software it showed the problems in the process of improvement of facilities layout should pay attention to. Finally in Thailand retail giants Lotus Supermarket in Hangzhou east district of peace square store as an example, it studied the improvement strategies of store overall facilities layout and procedures, then researched systematic facilities layout planning method, industrial engineering and computer simulation technology in process of improvement of facilities layout, expounded the key matter in its application can efficiently improve complete facilities layout, overcome the reverse logistics , ensure better, more perfect operation of retail.
KEYWORDS：systematic layout planning，industrial engineering， chain supermarket，Flexsim
