Title: Psychological care in improving stomach cancer patients perioperative anxiety and depression in application ABSTRACT Objective Explore stomach cancer patients perioperative anxiety psychological factors and psychological intervention on patients with cancer of the stomach perioperative care effect of anxiety and depression. Methods 80 cases of gastric cancer will surgery patients were randomly divided into trial group and control group in 40 cases 40 cases, the observation group using psychological care, control group was used by routine care method, the patients were depression (SDS) and anxiety from rating scale (SAS) evaluation, and in comparison of the nursing effect.. Results Application of depression and anxiety from rating scale (SDS, of 80 cancer of the stomach SAS) around the time of surgery patients for testing, complementary with self-designed questionnaire influence factors related factors to the disease, and surgery investigation of the fear and surgery, the effect, the medical atmosphere, family economic conditions, pain, the sleep quality, marriage, career affected, to know the degree, the worry about medical condition not elaborate ten of the factors and the anxiety of the state have significantly related. The observation group depression and anxiety index after the therapy before treatment than decreased significantly (P < 0.01), whereas the control after treatment than before treatment depression and anxiety exponential decline is not obvious (P > 0.05), after treatment of two index in the control group were significantly higher than that of the observation group (P < 0.05). Conclusion 1, stomach cancer patients perioperative depression anxiety and pain, to the disease and the operation to fear, worry about surgical treatment effects related to such factors. 2, to cancer of the stomach perioperative period in patients with psychological intervention, can effectively reduce the patients of depression and anxiety level, and clinical application.