Abstract Objective The complication rate using the full range of frozen and surgical treatment, by contrast to the same pathological type of liver cancer patients, patients satisfaction, patients 1 year and 3-year survival rate, select the more favorable treatment to patients. Methods Suffering from advanced liver cancer stay in hepatobiliary surgery needed to treat patients according to the selected treatment program into a full range of cryotherapy (freezing group) and conventional surgery group (surgery group), records were compared between the two groups of cases of postoperative complications occurred,follow-up investigation in patients 1 year and 5-year survival rate, evaluation of more effective treatment. Results (1) Compared the clinical data, including gender, incidence of origin of hepatitis B surface antibody, pathological stage of patients in the two groups, the difference was not significant (p> 0.05), showing that the two sets of clinical data was no significant difference,and was comparable. (2)The same pathological type, severity of disease is considerable in patients with advanced surgery and cryotherapy, two groups of patients with complication rate differences, cryotherapy Overall complication rate is lower than the surgical group. P < 0.05, the difference was statistically significant (3)Accept the freezing treatment, patient satisfaction with surgery than the conventional surgery group; P < 0.05, the difference was statistically significant. one year survival in two groups of patients is quite frozen in patients treated with 3-year survival rate is higher than the surgery alone group.. (4) Compared to conventional surgery, cryotherapy has the low incidence of complications, P <0.05, which difference has statistically significant. With long-term survival and quality of life, the cryotherapy is worthy promoting on patients with advanced hepatocellular carcinoma in the clinical treatment. Conclusions With advanced hepatocellular carcinoma in patients with a full range of cryotherapy and to take timely, safe and effective care can effectively prevent and reduce complications and improve patient and long term survival and quality of life, is a safe and effective treatment. Keywords Full range of cryotherapy; Surgery; With advanced hepatocellular carcinoma; Complications Paper type: clinical study 目 录 摘要………………………………………………………………………………… 1 前言………………………………………………………………………………14 1.1研究背景及意义 ………………………………………………………………14 1.2研究目的及目标 ………………………………………………………………15 1.2.1研究目的…………………………………………………………………… 15 1.2.2研究目标…………………………………………………………………… 16 1.3关键词及定义………………………………………………………………… 16 1.3.1全方位冷冻治疗…………………………………………………………… 16 1.3.2手术治疗…………………………………………………………………… 16 1.3.3中晚期肝癌……………………………………………………………… 16 1.3.4并发症……………………………………………………………………… 16 1.4文献回顾……………………………………………………………………… 17 1.4.1中晚期肝癌的判断标准…………………………………………………… 17 1.4.2 中晚期肝癌研究现状……………………………………………………… 17 1.4.3中晚期肝癌治疗方法……………………………………………………… 17 1.4.4 肝癌的手术治疗效果…………………………………………………… 18 2研究设计与方法…………………………………………………………………20 2.1研究设计………………………………………………………………………20 2.2研究对象………………………………………………………………………21 2.3研究步骤………………………………………………………………………21 2.4研究工具及方法………………………………………………………………21 2.5资料分析………………………………………………………………………22 3结果与分析………………………………………………………………………22 3.1试验组与对照组的临床资料的分析…………………………………………22 3.2两组术后并发症相关分析………………………… 23 3.3两组患者术后随访结果对比………………………23 4讨论 …………………………………………………………………………… 25 4.1 冷冻治疗肝癌…………………………………………………… 25 4.1.1 全方位冷冻治疗中晚期肝癌……………………………………………… 25 4.1.2 冷冻治疗的适应症及禁忌症……………………………………………… 25 4.1.3 冷冻治疗术后并发症及应对措施………………………………………… 25 4.2 手术治疗肝癌………………………………… 25 5 结论………………………………………………………………………………27 6 致谢………………………………………………………………………………28 参考文献………………………………………………………………………… 29 附表……………………………………………………………………………… 31
