关键词: 卵巢功能衰退，月经周期长度,平均SD 论文类型：前瞻性队列研究 Title: The Study on the Influential Factors and Nursing of BehaviorDisorders of Nephrotic Syndrome Children ABSTRACT Objective To analyze the relationship between the changes of menstruation(1ength of menstrual cycle and it’s veribility，length of mens and it’s veribility，menstrual blood loss and veribility)and the process of ovary aging． 1．To describe the changes of menstruation、with age increasing． 2．To describe the changes of menstruation with FSH increasing． 3．To choose a veribale of the changes of menstruation that can describe ovary aging used in clinics． Methods We analysis data of the baseline investigation and 1 2 monthsa：1 5 clays follow up．377 women aged 30—54 years who lived Bering community attended our survey by the purposive sample method．We conducted the survey by face-to-face interview with the questionnaire．The items of the queStionnaire are detailed as follow：the basic conditions (such as age，career,education,income，etc)，illness medical history，sex hormone treatment history，menstruation condition．1 2 months-a：1 5 days later these women were investigated again for changes of the above situations and re-measured the indexes below． Serum E2：Using the electrochemiluminescenc； Serum FSH：Using the electrochemiluminescenc； The biggest section proportion of ovary(BSPO). Results (1) Totally recorded menstrual cycles are 3596 with average lengths as 33．09±23．74 days (median 28 days). (2) The recorded mens are 391 9 totally，、^ritll average lengths as 4．70±2．09 days(median 4 days)．The percentage of regular menstrual cycle at baseline is 22．6％(73)，and no menstrual cycle longer than 1 80 days．At the 12th month,the percentage of regular menstrual cycle is l 7．3％(56)，and the menstrual cycle of 1 5 women(4．6％)>180 clays，8 women(2．5％)‘s menstrual cycle>365．FSH level at baseline(14．96±1 5．3 1 IU／L，median 8．74 IU／L) iS lower than follow up (19．78±21．14IU／L，median 9．86 IU／L)．E2 at baseline(73．67±75．83 pg／ml，median 52．20 pg／rrd)is higher than follow up(68．46±76．29pg／ml，median 45．90 pg／m1)．The right BSPO at baseline(3．49±1．20 cm2，median 3．34 cm2)is larger than follow up(3．27±1．28cm2，3．07 cm2)． Conclusion The length of menstrual cycle Was shortest in 40-42 years grou pwith lowes variability．The variability of menstrual cycle Was prolonged with the increase of age．The length of menstrual flow and its variability,the amount of menstrual loss and its variability did not show the trends、with age．The length and the variability of menstrual cycle could reflect the different levels of FSH．，nle length and the variability of menstrual cycle are the indicators of ovary aging·． Key words：Ovary aging，Menstruation，Variability
