The MIS system has already got an extensive usage in every trade, obtained good economy and the performance of management, in the meantime, the business enterprise manage of information-based is the marking of modern and successful business enterprise. Therefore manage the research of information system to have good actual usage value to the business enterprise. This topic aims at a circumstance of make the medicine business enterprise and the design developped a "enter to sell to save an information management system" which has basic function and carry out the modernization of management of the business enterprise information. That system adoption B/S structure, according to the WEB method, have an enter of business enterprise product, raw material to sell, stock management etc. operation. The system operation is simple, interface amity, vivid and practical, the safety be stable, basic match to make a medicine business enterprise into sell a request of save the information management.