Nowadays, improving dormitory management turns to the focal point in campuses. developing relevant Dormitory MIS Software ( Dormitory Management Information System Software) by computers and network has important significance. This thesis talked about the process of designing and developing the Dormitory MIS Software. Firstly, briefly introduce the background and significance of this Dormitory MIS Software. Then analysis the system including requirement analysis and feasibility analysis. Secondly, the system function is divided to nine functional modules which are system management, dormitory management, student residential management, report form, object management, maintenance management, visiting management, student information management and self-help management. And then, specifically record the process of developing system by SQL Server as DBMS (Database Management System) and PowerBuilder as develop tool. At the end, clear the function and orientate in future. The Dormitory MIS Software in this thesis is able to satisfy the need of actual dormitory management and make it automation and informatization.