Abstract: Compared with the type of paste modified natural, fewer researches are did in synthetic thickener in China, and little reported in the literature. There is a wide gap in the performance of thickener between foreign products and domestic products. In this paper, the synthesis conditions of polyacrylate thickeners include the various components of the dosage, reaction temperature, nitrogen ranked pass oxygen, holding time and other factors affected the performance of the thickener. Control the maximum reaction temperature at 75 ℃ and extend the reaction time at a relatively low temperature as long as possible. Use KPS as initiator, the amount in the quality of the monomer is 4 %; the proportion of transfer agent’s amount and emulsifier’s is close to 1:1; the usage of Acrylic Acid and Acrylamide in the ratio of 3.7:1 can reach the best overall performance for the better use of disperse dyes printing thickener.