Abstract: China is the foremost nation of footwear making and exporting. Facing the challenges such as the technology barrier in international commerce and the growth of footwear industries in Vietnam, India and other developing countries, it is a significant task for footwear industry of China to upgrade its technical innovation level. As a typical case of “development pattern of Wenzhou”, footwear industrial cluster in Wenzhou represents lots of features and drawbacks which other industries face. Basing upon CSP model and by analyzing the establishment and evolution of innovation system of industrial cluster in Wenzhou, this paper is to analyze and bring up a ladder to upgrade technical innovation in this cluster.