Study on the Synthesis, Characterization and Activity of Carboxymethylpachymaran
Abstract: In this study, we used chloroacetic acid to pachymaran carboxymethyl- ation under alkaline conditions. At the same time carboxymethyl polysaccharides were detected by biological activity, hydroxyl radical was producted by Feton reaction and carboxymethylation pachyman scavenging radical capacity was determined by salicylic acid color development process. It shows that the rate of hydroxyl radical scavenging effect of modified pachymaran is strengthened. By the experiments, carboxymethyl polysaccharides bile acid binding capacity increased significantly compared with unmodified ago. In addition, by measuring carboxymethyl polysaccharides solubility, degree of substitution, molecular weight and viscosity shows carboxymethyl polysaccharides successfully modified to one or more hydroxyl. These all above results provide a basis for future research.
Keywords:Carboxymethylpachymaran; Infrared spectrum; Bile acid binding; Viscosity ; DS