Study on the Catalysis Synthesis of Ethyl Salicylate
Abstract : This paper has carried on the orthogonal testing method to the conventional method as well as the microwave radiation synthesis of ethyl salicylate. This experiment used L16 (44) orthogonal table to complete the study of the catalysis synthesis of ethyl salicylate, and analysis of the experimental data for the optimized design . It investigated the yield of ester by using different proportion of salicylic acid and ethyl, different mix blend velocity, different quantity of sulfuric acid volume and different reaction time. The result enunciation that the most suitable and proper reaction conditions of the conventional method is that: the proportion of salicylic acid and ethyl is 1:9(the amount of salicylic acid is 0.05mol),mix blend the velocity is 150r/min, the sulfuric acid volume is 3.5 mL, and reaction time is 7 hours, and the ester produces a rate of 70.82%. The result enunciation that the most suitable and proper reaction conditions of the microwave radiation method is that:the proportion of salicylic acid and ethyl is 1:9(the amount of salicylic acid is 0.05mol),the powder is 325W,the sulfuric acid volume is 3.0 mL, and reaction time is 50 min, and the ester produces a rate of 73.75%. By comparison, the result shows that when microwave radiation technology was used in esterification, we can get short reaction times ,high yields,less byproducts and much more convenient in the process of after-treatment.
Keywords: Ethyl salicylate; Microwave radiation; Catalytic esterification; Orthogonal design