Abstract: this paper choose Sodium bisulfate monohydrate as the production catalyst for this design through comparison of a few catalysts. take the Sodium bisulfate monohydrate as catalyst and use the Acetic Anhydride, Salicylic acid as raw materials, to produce Aspirin. The craft process for Aspirin is a valid path of high produce, superior quality and low cost for the process is simple and product purity is high. We Designed a Production workshop for Aspirin of 1200 t/a for annual output, and studyed the materials, calories, body, the workshop decoration etc. According to the the process characteristics, we definite the reaction cycle for 14 hours each time, everyday 1 pass. According to the results of balance, We design the kettle ,also definite a Reactor of 6 cubic meters, two Crystalline kettle of 10 cubic meters, and a Refining Crystalline kettle of 10 cubic meters, though Mass Balance, quality that materials needed each time, and though Heat Balance, calories that needed to deliver, the design also included the body each parts of sizes and air dryer、cyclone and workshop layout, and so on. Finally, a flow chart of the reaction, a workshop layout diagram and a reaction kettle assembling drawing are given.
Keywords:Aspirin; Mass; Balance; Heat Balance; Kettle Design; Workshop Layout