Abstract: The conditions for extracting and the method for purifying flavonoids from myrica rubra leaves were studied in this article. And the main factors which effect the distill rate were also discussed. The results from L9(34)table shows that the extracting temperature was 60℃, the ratio of 50% ethanol to myrica rubra leaves was 20∶1, the time was 24 h. And the extractive ratio could be up to 7.532%, which was significantly higher than that under the Hypo - op timal conditions. And the extracts were further purified by silica gel column chromatography, the purity of the total flavonoids could be up to 92.32%. So the conditions above have some app lication value in industrial p rocessing of extracting total flavonoids from myrica rubra leaves.